RELEVANT PUBLICATIONS

Toth M. The other side of the coin: hypersociability. Genes Brain Behav. 2018 Aug 13:e12512. doi: 10.1111/gbb.12512.

Zupan B, Liu B, Taki F, Toth JG, and Toth M. Maternal brain TNF-a programs innate fear in the offspring. Curr Biol. 2017 Dec 18;27(24):3859-3863.e3. doi: 10.1016/j.cub.2017.10.071. 

Mitchell E, Klein SL, Argyropoulos KV, Sharma A, Chan RB, Toth JG, Barboza L, Bavley C, Bortolozzi A, Chen Q, Liu B, Ingenito J, Mark W, Dudakov J, Gross S, Di Paolo G, Artigas F, van den Brink M, and Toth M. Behavioural traits propagate across generations via segregated iterative-somatic and gametic epigenetic mechanismsNat Commun. 2016 May 13;7:11492. doi: 10.1038/ncomms11492.

Sharma A, Klein SS, Barboza L, Lohdi N, and Toth M. Principles Governing DNA Methylation during Neuronal Lineage and Subtype SpecificationThe Journal of Neuroscience, February 3, 2016 36(5):1711-1722

Zupan B, Sharma A, Frazier A, Klein S, and Toth M. Programming social behavior by the maternal fragile X proteinGenes Brain Behav. 2016 Jul;15(6):578-87. doi: 10.1111/gbb.12298. Epub 2016 Jun 10.. 

Toth M. Mechanisms of Non-Genetic Inheritance and Psychiatric DisordersNeuropsychopharmacology. 2014 Jun 3. doi: 10.1038/npp.2014.127. 

Abbott GW1, Tai KK, Neverisky DL, Hansler A, Hu Z, Roepke TK, Lerner DJ, Chen Q, Liu L, Zupan B, Toth M, Haynes R, Huang X, Demirbas D, Buccafusca R, Gross SS, Kanda VA, and Berry GT. KCNQ1, KCNE2, and Na+-coupled solute transporters form reciprocally regulating complexes that affect neuronal excitability. Sci Signal. 2014 Mar 4;7(315):ra22. doi: 10.1126/scisignal.2005025. 

Liu B, Zupan B, Laird E, Klein S, Gleason G, Bozinoski M, Gal Toth J and Toth M. Maternal hematopoietic TNF, via milk chemokines, programs hippocampal development and memoryNat Neurosci. 2014 Jan;17(1):97-105. 

Li Q, Bian S, Liu B, Hong J, Toth M and Sun T. Establishing brain functional laterality in adult mice through unilateral gene manipulation in the embryonic cortexCell Res. 2013 Sep;23(9):1147-9. 

Oh JE, Chambwe N, Klein S, Gal J, Andrews S, Gleason G, Shaknovich R, Melnick A, Campagne F, and Toth M. Differential gene body methylation and reduced expression of cell adhesion and neurotransmitter receptor genes in adverse maternal environmentTranslational psychiatry 2013 Jan 22;3:e218.

Hartrampf S, Dudakov JA, Johnson LK, Smith OM, Tsai J, Singer NV, West ML, Hanash A, Albert MH, Liu BF, Toth M, and van den Brink MRM. The Central Nervous System is a Target of Acute Graft-Versus-Host DiseaseBlood, 2013 Mar 7;121(10):1906-10.

Bortolozzi A, Castan J, Semakova A, Santana N, Alvarado G, Cortes R, Ferres-Coy A, Fernandez G, Carmona MC, Toth M, Perales JC, Montefeltro A and Artigas F. Selective siRNA-mediated suppression of 5-HT1A autoreceptors evokes strong anti-depressant-like effectsMol. Psychiatry. 2011. advance online publication 2 August 2011.

Gleason G, Liu B, Bruening S, Zupan B, Auerbach A, Mark W, Oh JE, Gal-Toth J, Lee F and Toth M. The serotonin1A receptor gene as a genetic and prenatal maternal environmental factor in anxietyProc Natl Acad Sci U S A. 2010 Apr 20;107(16):7592-7.

Zupan B and Toth M. Wild type male offspring of fmr-1+/- mothers exhibit characteristics of the fragile x phenotype.  Neuropsychopharmacology. 2008 Oct;33(11):2667-75.

Weisstaub NV, Zhou M, Lira A, Lambe E, González-Maeso J, Hornung JP, Sibille E, Underwood M, Itohara S, Dauer WT, Ansorge MS, Morelli E, Mann JJ, Toth M, Aghajanian G, Sealfon SC, Hen R, Gingrich JA. Cortical 5-HT2A Receptor Signaling Modulates Anxiety-Like Behaviors in MiceScience, 313(5786):536-40, 2006.

Kushnir-Sukhov NM, Gilfillan AM, Coleman JW, Brown JM, Bruening S, Toth M, and Metcalfe DD. 5-hydroxytryptamine induces mast cell adhesion and migrationJ. Immunology, 177:6422-6432, 2006.

Chen ZY, Jing D, Bath KG, Ieraci A, Khan T, Siao CJ, Herrera DG, Toth M, Yang C, McEwen BS, Hempstead BL, and Lee FS. Genetic Variant BDNF (Val66Met) Polymorphism Alters Anxiety-related BehaviorScience, 314:140-3, 2006.

Baile  SJ and Toth M. Variability in the benzodiazepine response of serotonin 5-HT1A receptor null mice displaying anxiety-like phenotype: evidence for genetic modifiers in the 5-HT mediated regulation of GABAA receptorsJ. Neuroscience. 24:6343-6351, 2004. PMID: 15254090.

Liu W, Seto J, Donovan G, and Toth M. Jerky, a protein deficient in a mouse epilepsy model, is associated with translationally inactive mRNA in neurons. J. Neuroscience 22: 176-182, 2002. PMID: 11756500.

Sibille E, Pavlides C, Benke D, and Toth M. Genetic inactivation of the 5-HT1A receptor in mice results in down-regulation of major GABAA receptor subunits, reduction of GABAA receptor binding, and benzodiazepine-resistant anxietyJ. Neuroscience 20, 2758-2765, 2000. PMID: 10751426.

Sarnyai Z, Sibille E, Pavlides C, McEwen B, and Toth M. Functional abnormalities in the hippocampus and impaired hippocampal-dependent learning in mice lacking the 5HT1A receptorsProc. Natl. Acad. Sci. USA. 97, 14731-14736, 2000. PMID: 11121072.

Parks C, Sibille E, Robinson T, Shenk T, and Toth M. Anxiety of mice lacking the serotonin1A receptorProc. Natl. Acad. Sci. USA. 95,10734-10739, 1998. PMID: 9724773.

Grimsby J, Toth M, Chen K, Kumazawa T, Klaidman L, Adams JD, Karoum K, Gal J, and Shih JC. Increased stress response and beta-phenylethylamine in MAOB-deficient miceNature Genetics 17, 206-210, 1997. PMID: 9326944.

Toth M, Grimsby J, Buzsaki G, Donovan, GP. Epileptic seizures caused by inactivation of a novel gene, jerky, related to centromere binding protein–B in transgenic miceNature Genetics 11, 71-75, 1995. PMID: 7550318.

Kochanek S, Toth M, Dehmel A, Rehr O, and Doerfler W. Interindividual concordance of methylation profiles in human genes for tumor necrosis factors alpha and betaProc. Natl. Acad. Sci. USA. 87: 8830-8834, 1990. PMID: 2247453.

Toth M, Lichtenberg U, and Doerfler W. Genomic sequencing reveals a 5-methyldeoxycytosine-free domain in active promoters and the spreading of preimposed methylation patternsProc. Natl. Acad. Sci. USA. 86: 3728-3732, 1989. PMID: 2524831.